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Viable acrosome-intact human spermatozoa in the ejaculate as a marker of semen quality and fertility

Dorte Louise Egeberg Palme1, Anders Rehfeld1, Anne Kirstine Bang1, Kristiana Alexandrova Nikolova1, Søren Kjærulff2, Morten Rønn Petersen3, Janni Vikkelsø Jeppesen3,



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Abstract:

STUDY QUESTION: Is it possible, in an unbiased and clinical relevant way, to determine the number of viable acrosome-intact human

spermatozoa in ejaculates and to use this as a measure of fertility chances?

SUMMARY ANSWER: Image cytometry enables easy and unbiased quantification of viable acrosome-intact spermatozoa and it correlates

with semen quality and fertility status.


keywords: acrosome / image cytometry / human semen quality / fertilization / infertility